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Rhizopus stolonifer (Ehrenberg : Fries) Lind
Rhizopus stolonifer (Ehrenberg : Fries) Lind
規(guī)格:
貨期:
編號(hào):B167272
品牌:Mingzhoubio

標(biāo)準(zhǔn)菌株
定量菌液
DNA
RNA

規(guī)格:
凍干粉
斜面
甘油
平板


產(chǎn)品名稱 Rhizopus stolonifer (Ehrenberg : Fries) Lind
商品貨號(hào) B167272
Deposited As Rhizopus nigricans Ehrenberg, teleomorph
Strain Designations C-25B [CBS 382.52, IFO 5781, IFO 6154, IFO 6300, IMI 57762, VKM F-401]
Application
produces 11-alpha-hydroxylase
produces 17 beta-hydroxysteroid dehydrogenase Estradiol 17-beta-dehydrogenase-1, Hydroxysteroid dehydrogenase 17 beta, type 1, hydroxysteroid 17-beta dehydrogenase 1
produces chiral alcohols
produces steroids
transformation of sesquiterpene lactone costunolide
reduces 3-methoxy-8(14)-seco-1,3,5(10),9(11)-estratetraene-14,17-dione
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format freeze-dried
Type Strain no
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Preceptrol® no
Mating Type mating type plus
Comments
Hydroxylation of 17 alpha-ethynyl steroids
Detoxification of steroids by cytochrome P45011alpha
Medium ATCC® Medium 336: Potato dextrose agar (PDA)
Growth Conditions
Temperature: 24.0°C
Name of Depositor AF Blakeslee
Cross References

Nucleotide (GenBank) : Y10414 R.nigricans mRNA for stress protein.

Nucleotide (GenBank) : S50228 steroid hydroxylase cytochrome P-450 [Rhizopus nigricans, ATCC

References

Abul-Hajj YJ. Stereochemistry of C-1, 2 dehydrogenation of 5 beta-pregnane-3, 11, 20-trione by Septomyxa affinis. J. Biol. Chem. 247: 686-691, 1972. PubMed: 5058221

Zakelj-Mavric M, et al. The bioconversion of 17 alpha-ethynyl steroids with 11 alpha-hydroxylase of Rhizopus nigricans. FEMS Microbiol. Lett. 33: 117-120, 1986.

Mills JS. 10-Fluoro-19-nor steroids. US Patent 3,053,858 dated Sep 11 1962

Gibian H, et al. Production of optically active antipodes. US Patent 3,562,112 dated Feb 9 1971

Lanisnik T, et al. Fungal 17 beta-hydroxysteroid dehydrogenase. FEMS Microbiol. Lett. 78: 49-52, 1992. PubMed: 1334892

Breskvar K, et al. The role of cytochrome P450(11 alpha) in detoxification of steroids in the filamentous fungus Rhizopus nigricans. J. Steroid Biochem. Mol. Biol. 52: 271-275, 1995. PubMed: 7696148

Hudnik-Plevnik T, Cresnar B. Factors affecting the induction of 11 alpha-hydroxylase of progesterone in the filamentous fungus Rhizopus nigricans. J. Steroid Biochem. 35: 749-751, 1990. PubMed: 2362437

Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979.

Kasai M, et al. Enantioselective ester hydrolyses using Rhizopus nigricans: stereoselective synthesis and absolute stereochemistry of (-)-cis-and (-)-trans-1-hydroxy-4-methyl-1,2,3,4-tetrahydronaphthalene. Can. J. Chem. 63: 1287-1291, 1985.

Zakelj-Mavric M, Belic I. Hydroxylation of steroids with 11alpha-hydroxylase of Rhizopus nigricans. J. Steroid Biochem. 28: 197-201, 1987. PubMed: 3498094

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